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KMID : 1134819970260030488
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Journal of the Korean Society of Food Science and Nutrition
1997 Volume.26 No. 3 p.488 ~ p.493
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Effects of Extract of Pueraria radix on Hematological Properties and Lead Level of the Tissues of the Pb - administered Rats
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Lee Jeong-Sook
Kim Myung-Joo
Park Eun-Mi
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Abstract
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This study was designed to investigate the effects of Korean Pueraria radix extract in Pb administered rats. Pb exposed rats were given 1% Pb in the diet. δ-Aminolevulinic acid(DALA) and urinary glucose levels were increased with Pb administration and were lower in the Pb group than in the group administered Pb alone. Hematocrit value was decreased with Pb administration and was higher in the Pb group than in the C-Pb group. δ-Aminolevulinic acid dehydratase(DALAD) activity was decreased in the Pb group. ALT and AST were increased by Pb added and were lower in the Pb group than in the C-Pb group. Serum Pb content was higher in the Pb exposed rats than in the control groups, and no significant difference was found due to extract of Pueraria radix supplementation. Levels of liver, kidney and femur lead were reduced by Pueraria radix. Lead contents in feces and urine were higher in the Pb added groups than in the control group, and level of feces lead was increased by extract of Pueraria radix.
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KEYWORD
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lead, Pueraria radix, $\delta$-aminolevulinic acid dehydratase(DALAD) activity
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